Diario Médico reports on the presentation of the Lilly Foundation's 2016 Preclinical Biomedical Research Award to Eduard Batlle, head of the Colorectal Cancer Lab at IRB Barcelona.
Press release: Eduard Batlle awarded the Lilly Foundation's 2016 Biomedical Research Award
Mutations in cancer genomes: foggy with a chance of thunderstorms
The mechanism unveiled triggers a mutation fog, causing hundreds of mutations in each tumor, which spread through the genome of lung, head-and-neck and breast cancers.
Researchers from the Genome Data Science Lab have identified the antiviral APOBEC3A enzyme as the major cause of this new type of hypermutation.
Published in Nature Genetics, the study shows how the mutation fog process generates many oncogenic “cancer driver” mutations, thus accelerating tumour development.
Identification of a determining factor in luminal cancer cells, that cause the greatest number of breast cancer cases
Researchers at IRB Barcelona discover a new mechanism in estrogen receptor-positive breast cancer cells.
The inhibition of CPEB2, a key factor in the estrogen signalling pathway, causes cancer cells to proliferate less and protects mice against luminal breast cancer.
An interview with Clara Morral, Postdoctoral Fellow at IRB Barcelona
Clara Morral is the first author of an article recently published in the scientific journal Cell Stem Cell.
The study identifies that protein synthesis is a key property for the regenerative potential of colon cancer cells.