Immunotherapy against cancer
The Heraldo newspaper has published an article about the role of immunotherapy to rearm patients’ defences and contribute to the fight against cancer. In the article, the authors mention the work of Eduard Batlle, ICREA researcher at IRB Barcelona, on the effectiveness that enhances immune system function in colon cancer.
Link to Heraldo
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Several media channels have reported on the award of European Research Council funding to various projects being undertaken in Catalonia. Among these projects is that of Eduard Batlle, head of the Colorectal cancer Lab at IRB Barcelona. His research will focus on the hidden cells of the primary tumour that begin to spread before surgical intervention and that can remain undetectable for months or years until they seed a new tumour.
Batlle will study the distinct mechanisms through which these cells evade the immune system and invade another organ.
Published in the journal Nature Cancer, the study analyses how genetic alterations in tumour cells prevent the correct degradation of the proteins involved in tumour development and growth, thereby leading to abnormal cell behaviour.
A machine-learning model has allowed the scientists to obtain the most extensive annotation of the ubiquitin-mediated protein degradation system.
The analysis proposes a potential new clinical approach for cancer through the inhibition of oncoproteins with impaired degradation systems.
The newspaper La Tribuna de Albacete has interviewed IRB Barcelona researcher Erika López Arribillaga about a grant awarded to her on 24 September by the Spanish Association Against Cancer (AECC). López Arribillaga’s project aims to unravel the long-term effects of some chemotherapy treatments on colorectal cancer patients.
Link to La Tribuna de Albacete
