Several specialized websites have echoed the review article on Mitochondrial Dynamics headed by researchers at IRB Barcelona and Biomedical Research Networking Center in Diabetes and Associated Metabolic Disorders (CIBERDEM).
Aging is associated with a decline in mitochondrial function and accumulation of abnormal mitochondria. In this work, published in Trends in Molecular Medicine (Cell Press), David Sebastián, Manuel Palacín and Antonio Zorzano, summarize information about mitochondrial dynamics proteins and their role in the regulation of mitochondrial fitness and their relation to age-related diseases.
The scientists propose that alterations in proteins involved in mitochondrial dynamics during aging is the origin of the accumulation of damaged and dysfunctional mitochondria, and this contributes to age-related disorders.
Other media mentions
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