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Two studies show that CRISPR works better in cells more prone to mutations

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The newspaper El País has published an article about the implications of applying the CRISPR-Cas9 technique in human cells that could facilitate the appearance of tumours, according to two articles published in the journal Nature Medicine. The journalist interviewed Manuel Serrano, head of the Cellular Plasticity and Disease Lab at IRB Barcelona, who does not consider that these results are completely pessimistic because "Once a genetic defect has been corrected, it can be verified if these cells maintain p53, so we will have to add another quality test to use the cells that maintain it and not the others ".

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About IRB Barcelona

The Institute for Research in Biomedicine (IRB Barcelona) pursues a society free of disease. To this end, it conducts multidisciplinary research of excellence to cure cancer and other diseases linked to ageing. It establishes technology transfer agreements with the pharmaceutical industry and major hospitals to bring research results closer to society, and organises a range of science outreach activities to engage the public in an open dialogue. IRB Barcelona is an international centre that hosts 400 researchers and more than 30 nationalities. Recognised as a Severo Ochoa Centre of Excellence since 2011, IRB Barcelona is a CERCA centre and member of the Barcelona Institute of Science and Technology (BIST).