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Research

At the forefront of biomedicine

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Manuel Serrano

Unit:
Position:
Group Leader
Office:
EM01C42-44
Telephone:
+34 93 40 20287

ICREA Research Professor, ERC Advanced Grant, "la Caixa" Foundation

ICREA
Research Group

Current researcher's video

Selected group publications

Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19
Bernad R; Lynch CJ; Urdinguio RG; Stephan-Otto Attolini C; Fraga MF; Serrano M
Cells
10
(4 )
-
(2021)
In Vivo Reprogramming Ameliorates Aging Features in Dentate Gyrus Cells and Improves Memory in Mice
Rodríguez-Matellán A; Alcazar N; Hernández F; Serrano M; Ávila J
Stem Cell Reports
15
(5 )
1056 -
1066
(2020)
Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases
Lynch CJ; Bernad R; Martínez-Val A; Shahbazi MN; Nóbrega-Pereira S; Calvo I; Blanco-Aparicio C; Tarantino C; Garreta E; Richart-Ginés L; Alcazar N; Graña-Castro O; Gómez-Lopez G; Aksoy I; Muñoz-Martín M; Martinez S; Ortega S; Prieto S; Simboeck E; Camasses A; Stephan-Otto Attolini C; Fernandez AF; Sierra MI; Fraga MF; Pastor J; Fisher D; Montserrat N; Savatier P; Muñoz J; Zernicka-Goetz M; Serrano M
Nature Cell Biology
22
(10 )
1223 -
1238
(2020)
Manipulating the Mediator complex to induce naïve pluripotency
Lynch CJ; Bernad R; Calvo I; Serrano M
Experimental Cell Research
395
(2 )
112215 -
(2020)
Induction of lysosome membrane permeabilization as a therapeutic strategy to target pancreatic cancer stem cells
Cash TP; Alcalá S; Rico-Ferreira MDR; Hernández-Encinas E; García J; Albarrán MI; Valle S; Muñoz J; Martínez-González S; Blanco-Aparicio C; Pastor J; Serrano M; Sainz B
Cancers
12
(7 )
1 -
25
(2020)