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Research

At the forefront of biomedicine

Dr. Manuel Serrano

Unit:
Position:
Affiliated Group Leader
Office:
EM01C42-44
Research Group

Current researcher's video

Selected group publications

Cellular senescence is immunogenic and promotes anti-tumor immunity
Marin I, Boix O, Garcia-Garijo A, Sirois I, Caballe A, Zarzuela E, Ruano I, Attolini CS, Prats N, López-Domínguez JA, Kovatcheva M, Garralda E, Muñoz J, Caron E, Abad M, Gros A, Pietrocola F, Serrano M
Cancer Discovery
13
(2 )
410 -
431
(2023)
Deciphering the roadmap of in vivo reprogramming toward pluripotency
Chondronasiou D, Martínez de Villarreal J, Melendez E, Lynch CJ, Pozo ND, Kovatcheva M, Aguilera M, Prats N, Real FX, Serrano M
Stem Cell Reports
17
(11 )
2501 -
2517
(2022)
The lysosomal proteome of senescent cells contributes to the senescence secretome
Rovira M, Sereda R, Pladevall-Morera D, Ramponi V, Marin I, Maus M, Madrigal-Matute J, Díaz A, García F, Muñoz J, Cuervo AM, Serrano M
Aging Cell
21
(10 )
e13707 -
e13707
(2022)
Natural killer cells act as an extrinsic barrier for in vivo reprogramming
Melendez, E; Chondronasiou, D; Mosteiro, L; de Villarreal, JM; Fernandez-Alfara, M; Lynch, CJ; Grimm, D; Real, FX; Alcami, J; Climent, N; Pietrocola, F; Serrano, M
Development
149
(8 )
dev200361 -
(2022)
Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming
Chondronasiou, D; Gill, D; Mosteiro, L; Urdinguio, RG; Berenguer, A; Aguilera, M; Durand, S; Aprahamian, F; Nirmalathasan, N; Abad, M; Martin-Herranz, DE; Otto-Attolini, CS; Prats, N; Kroemer, G; Fraga, MF; Reik, W; Serrano, M
Aging Cell
21
(3 )
e13578 -
(2022)