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Research

At the forefront of biomedicine

Research publications

Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling
Solanas, G; Cortina, C; Sevillano, M; Batlle, E
Nature Cell Biology
13
9
1100 -
U128
2011
A smad action turnover switch operated by WW domain readers of a phosphoserine code
Aragón, E; Goerner, N; Zaromytidou, AI; Xi, QR; Escobedo, A; Massagué, J; Macias, MJ
Genes & Development
25
12
1275 -
1288
2011
Drosophila neuroblasts retain the daughter centrosome
Januschke, J; Llamazares, S; Reina, J; Gonzalez, C
Nature Communications
2
1
243 -
2011
Distributed biological computation with multicellular engineered networks
Regot S; MacIa J; Conde N; Furukawa K; Kjellén J; Peeters T; Hohmann S; De Nadal E; Posas F; Solé R
Nature
469
7329
207 -
211
2011
The structure of a transcription activation subcomplex reveals how sigma(70) is recruited to PhoB promoters
Blanco, AG; Canals, A; Bernués, J; Solà, M; Coll, M
Embo Journal
30
18
3776 -
3785
2011
The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
Merlos-Suárez, A; Barriga, FM; Jung, P; Iglesias, M; Céspedes, MV; Rossell, D; Sevillano, M; Hernando-Momblona, X; da Silva-Diz, V; Muñoz, P; Clevers, H; Sancho, E; Mangues, R; Batlle, E
Cell Stem Cell
8
5
511 -
524
2011
DDOR is an EcR coactivator that forms a feed-forward loop connecting insulin and ecdysone signaling
Francis, VA; Zorzano, A; Teleman, AA
Current Biology
20
20
1799 -
1808
2010
Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1α/mitofusin-2 regulatory pathway in response to physical activity
Hernández-Alvarez, MI; Thabit, H; Burns, N; Shah, S; Brema, I; Hatunic, M; Finucane, F; Liesa, M; Chiellini, C; Naon, D; Zorzano, A; Nolan, JJ
Diabetes Care
33
3
645 -
651
2010
Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila
Janic, A; Mendizabal, L; Llamazares, S; Rossell, D; Gonzalez, C
Science
330
6012
1824 -
1827
2010
A dp53-dependent mechanism involved in coordinating tissue growth in Drosophila
Mesquita, D; Dekanty, A; Milán, M
Plos Biology
8
12
e1000566 -
2010
Hepatic overexpression of a constitutively active form of liver glycogen synthase improves glucose homeostasis
Ros, S; Zafra, D; Valles-Ortega, J; García-Rocha, M; Forrow, S; Domínguez, J; Calbó, J; Guinovart, JJ
Journal Of Biological Chemistry
285
48
37170 -
37177
2010
Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat
Jiménez-Menéndez, N; Fernández-Millán, P; Rubio-Cosials, A; Arnan, C; Montoya, J; Jacobs, HT; Bernadó, P; Coll, M; Usón, I; Solà, M
Nature Structural & Molecular Biology
17
7
891 -
893
2010
The miRNA machinery targets Mei-P26 and regulates Myc protein levels in the Drosophila wing
Herranz, H; Hong, X; Pérez, L; Ferreira, A; Olivieri, D; Cohen, SM; Milán, M
Embo Journal
29
10
1688 -
1698
2010
Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control
Novoa, I; Gallego, J; Ferreira, PG; Mendez, R
Nature Cell Biology
12
5
447 -
U82
2010
A Role of Receptor Notch in Ligand cis-Inhibition in Drosophila
Becam, I; Fiuza, UM; Arias, AM; Milán, M
Current Biology
20
6
554 -
560
2010
Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses
Geslain, R; Cubells, L; Bori-Sanz, T; Alvarez-Medina, R; Rossell, D; Martí, E; de Pouplana, LR
Nucleic Acids Research
38
5
e30 -
e30
2010
Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain
Nadal, M; Mas, PJ; Blanco, AG; Arnan, C; Solà, M; Hart, DJ; Coll, M
Proceedings Of The National Academy Of Sciences Of The United States Of America
107
37
16078 -
16083
2010
Self-killing of melanoma cells by cytosolic delivery of dsRNA: Wiring innate immunity for a coordinated mobilization of endosomes, autophagosomes and the apoptotic machinery in tumor cells
Alonso-Curbelo D, Soengas MS
Autophagy
2010
The Ink4/Arf locus is a barrier for iPS cell reprogramming
Li, Han; Collado, Manuel; Villasante, Aranzazu; Strati, Katerina; Ortega, Sagrario; Canamero, Marta; Blasco, Maria A; Serrano, Manuel
Nature
460
7259
1136 -
U101
2009
Focus on the centre: The role of chromatin on the regulation of centromere identity and function
Torras-Llort, M; Moreno-Moreno, O; Azorín, F
Embo Journal
28
16
2337 -
2348
2009
Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure
Solon, J; Kaya-Çopur, A; Colombelli, J; Brunner, D
Cell
137
7
1331 -
1342
2009
Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells
Tormo D, Checińska A, Alonso-Curbelo D, Pérez-Guijarro E, Cañón E, Riveiro-Falkenbach E, Calvo TG, Larribere L, et al, [corr. author] Soengas MS.
Cancer Cell
2009
An Operational RNA Code for Faithful Assignment of AUG Triplets to Methionine
Jones, TE; Brown, CL; Geslain, R; Alexander, RW; De Pouplana, LR
Molecular Cell
29
3
401 -
407
2008
Drosophila HP1c isoform interacts with the zinc-finger proteins WOC and Relative-of-WOC to regulate gene expression
Font-Burgada, J; Rossell, D; Auer, H; Azorín, F
Genes & Development
22
21
3007 -
3023
2008
Spindle-localized CPE-mediated translation controls meiotic chromosome segregation
Eliscovich, C; Peset, I; Vernos, I; Méndez, R
Nature Cell Biology
10
7
858 -
865
2008
A deadenylation negative feedback mechanism governs meiotic metaphase arrest
Belloc, E; Méndez, R
Nature
452
7190
1017 -
U11
2008
The fission yeast homologue of CENP-B, Abp1, regulates directionality of mating-type switching
Aguilar-Arnal, L; Marsellach, FX; Azorín, F
Embo Journal
27
7
1029 -
1038
2008
A Combinatorial Code for CPE-Mediated Translational Control
Piqué, M; López, JM; Foissac, S; Guigó, R; Méndez, R
Cell
132
3
434 -
448
2008
A Wingless and Notch double-repression mechanism regulates G1-S transition in the Drosophila wing.
Herranz, H; Pérez, L; Martín, FA; Milán, M
Embo Journal
27
11
1633 -
1645
2008
Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy
Vilchez, D; Ros, S; Cifuentes, D; Pujadas, L; Vallès, J; García-Fojeda, B; Criado-García, O; Fernández-Sánchez, E; Medraño-Fernández, I; Domínguez, J; García-Rocha, M; Soriano, E; De Córdoba, SR; Guinovart, JJ
Nature Neuroscience
10
11
1407 -
1413
2007
Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
Caussinus E; Gonzalez C
Nature Genetics
37
10
1125 -
1129
2005