Biostatistics/Bioinformatics
Meet Our Scientists Videos
Research information
Background
The mission of the Biostatistics/Bioinformatics Unit is to conduct collaborative research and to provide consultation and quantitative research resources to all IRB Barcelona research groups.
We assist scientists by providing both short and long-term consultancy services in the following areas:
- Experimental design: sample size, study design, planning of statistical methodology
- Data analysis: clinical or biomedical databases, genomics data
- Assistance with statistical methodology in own or others’ research
- Software: help in using software, develop software to meet special data analysis or study design needs
The facility conducts methodological research and develops resources in all of the above-mentioned areas.
For more information contact the manager of the Biostatistics/Bioinformatics Unit at
camille.stephan
irbbarcelona.org.
Selected publications
Projects
CERCAGINYS és la plataforma d’accés a les infraestructures científiques i tècniques dels 41 centres CERCA. La iniciativa vol optimitzar l’accés a aquestes instal·lacions per a tota la comunitat científica i tecnològica i, molt especialment, vol evidenciar la possibilitat que el sector privat empresarial i industrial també pot fer-ne ús, accedint, així mateix, als serveis de personal tècnic altament qualificat. La proposta forma part d’un projecte més ampli, vinculat al Pla d’Acció d’Infraestructures finançat pel Ministeri de Ciència i Innovació a través de la I-CERCA.
Services
- Microarrays: Quality control, Differential expression, Enrichment analysis of GO and KEGG, GSEA GO and KEGG, Signature discovery
- RNASeq: Quality control, Differential expression, Enrichment analysis of GO and KEGG, Signature discovery, Isoform switching, SNP calling
- ChipSeq: Processing, Quality control, Peak definition + annotation + visualization, Differential Binding + Integrative analysis
- Whole Genome Sequencing: Processing, Quality control, SNP calling, Copy number alteration calling
- Whole Exome Sequencing: Processing, Quality control, SNP calling, Copy number alteration calling
- Proteomics: Processing, Quality control, Differential expression, Enrichment analysis of GO and KEGG
- Public database mining and analysis: Selection, Curation of clinical data, Processing of expression data, Association of expression and clinical data, Integration of copy number/genomic data
- TCGA analysis: Exploratory analysis in all cancer types: association between expression and clinical variables, Detailed analysis with curated clinical and technical variables: association with expression, Data integration: copy number, expression, mutations, etc
- Microbiome: Quality control + OTU estimation + differential abundance, Phylogenetic analysis
- Binding prediction: Prediction of binding to RNA/DNA by proteins/genes
- Single Cell Sequencing: Processing, Quality control, Differential expression, Clustering, Trajectories, Enrichment analysis of GO and KEGG
- Consulting: Statistical consulting, Data analysis, Custom services
- Experimental design
