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Core Facilities & Services
Biostatistics/Bioinformatics

Research information

Background

The mission of the Biostatistics/Bioinformatics Unit is to conduct collaborative research and to provide consultation and quantitative research resources to all IRB Barcelona research groups.

We assist scientists by providing both short and long-term consultancy services in the following areas:

  • Experimental design: sample size, study design, planning of statistical methodology 
  • Data analysis: clinical or biomedical databases, genomics data
  • Assistance with statistical methodology in own or others’ research
  • Software: help in using software, develop software to meet special data analysis or study design needs

The facility conducts methodological research and develops resources in all of the above-mentioned areas.

For more information contact the manager of the Biostatistics/Bioinformatics Unit at
camille.stephanarrobairbbarcelona.org. 

Selected publications

Cortina C; Turon G; Stork D; Hernando-Momblona X; Sevillano M; Aguilera M; Tosi S; Merlos-Suárez A; Stephan-Otto Attolini C; Sancho E; Batlle E
Embo Molecular Medicine
9
(7 )
869 -
879
(2017)
Barriga F; Montagni E; Mana M; Mendez-Lago M; Hernando-Momblona X; Sevillano M; Guillaumet-Adkins A; Rodriguez-Esteban G; Buczacki S; Gut M; Heyn H; Winton D; Yilmaz O; Attolini C; Gut I; Batlle E
Cell Stem Cell
20
(6 )
801 -
816.e7
(2017)
Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L, Benitah SA
Nature
541
(7635 )
41-45 -
+
(2017)
Stephan-Otto Attolini C; Peña V; Rossell D
Bioinformatics
31
(22 )
3631 -
3637
(2015)
Torres A; Piñeyro D; Rodríguez-Escribà M; Camacho N; Reina O; Saint-Léger A; Filonava L; Batlle E; Ribas De Pouplana L
Nucleic Acids Research
43
(10 )
5145 -
5157
(2015)
Kessler R; Tisserand J; Font-Burgada J; Reina O; Coch L; Attolini CSO; Garcia-Bassets I; Azorín F
Nature Communications
6
(7049 )
7049 -
(2015)
Calon A; Lonardo E; Berenguer-Llergo A; Espinet E; Hernando-Momblona X; Iglesias M; Sevillano M; Palomo-Ponce S; Tauriello D; Byrom D; Cortina C; Morral C; Barceló C; Tosi S; Riera A; Attolini C; Rossell D; Sancho E; Batlle E
Nature Genetics
47
(4 )
320 -
329
(2015)
Whissell, Gavin; Montagni, Elisa; Martinelli, Paola; Hernando-Momblona, Xavier; Sevillano, Marta; Jung, Peter; Cortina, Carme; Calon, Alexandre; Abuli, Anna; Castells, Antoni; Castellvi-Bel, Sergi; Nacht, Ana Silvina; Sancho, Elena; Stephan-Otto Attolini, Camille; Vicent, Guillermo P; Real, Francisco X; Batlle, Eduard
Nature Cell Biology
16
(7 )
695 -
707
(2014)
Cuartero S; Fresán U; Reina O; Planet E; Espinàs M
Embo Journal
33
(6 )
637 -
647
(2014)
Font-Burgada J; Reina O; Rossell D; Azorín F
Nucleic Acids Research
42
(4 )
2126 -
2137
(2014)
Planet E; Attolini C; Reina O; Flores O; Rossell D
Bioinformatics
28
(4 )
589 -
590
(2012)

Services

  • Microarrays: Quality control, Differential expression, Enrichment analysis of GO and KEGG, GSEA GO and KEGG, Signature discovery
  • RNASeq: Quality control, Differential expression, Enrichment analysis of GO and KEGG, Signature discovery, Isoform switching, SNP calling
  • ChipSeq: Processing, Quality control, Peak definition + annotation + visualization, Differential Binding + Integrative analysis
  • Whole Genome Sequencing: Processing, Quality control, SNP calling, Copy number alteration calling
  • Whole Exome Sequencing: Processing, Quality control, SNP calling, Copy number alteration calling
  • Proteomics: Processing, Quality control, Differential expression, Enrichment analysis of GO and KEGG
  • Public database mining and analysis: Selection, Curation of clinical data, Processing of expression data, Association of expression and clinical data, Integration of copy number/genomic data
  • TCGA analysis: Exploratory analysis in all cancer types: association between expression and clinical variables, Detailed analysis with curated clinical and technical variables: association with expression, Data integration: copy number, expression, mutations, etc
  • Microbiome: Quality control + OTU estimation + differential abundance, Phylogenetic analysis
  • Binding prediction: Prediction of binding to RNA/DNA by proteins/genes
  • Single Cell Sequencing: Processing, Quality control, Differential expression, Clustering, Trajectories, Enrichment analysis of GO and KEGG
  • Consulting: Statistical consulting, Data analysis, Custom services
  • Experimental design

Consult the service rates

Group members

Core Facility Manager
Senior Research Officer
Research Officer
Research Officer
Trainee M4L

Group News

Media mentions
22 Jan 2010

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