A molecular shuttle for Friedreich’s ataxia

Image: Julio Carbó.

Image: Julio Carbó.


The newspaper "El Periódico" has reported on an IRB Barcelona research project on Friedreich’s ataxia disease, funded by the patient and family association, the Babel Family, and the Asociación Granadina de la Ataxia de Friedreich (ASOGAF). The disease is caused by a defect in a gene, frataxin, which results in reduced levels of this protein in the body, particularly affecting the brain, spinal cord and muscles.

The project aims to develop an injectable frataxin treatment that can reach the brain, "like the injection of insulin for diabetics", explains Ernest Giralt, head of the Design, Synthesis and Structure of Peptides and Proteins Laboratory at IRB Barcelona and coauthor of the study with research associates Meritxell Teixidó and Macarena Sánchez.

Link to  El Periódico