El Plural has published an article on the project being undertaken by Gonzalo Fernández-Miranda, an associate researcher at IRB Barcelona. The project seeks to develop a better treatment for cancer of the head and neck by means of an immunotherapeutic approach, which has been validated with proof of concept tests at the genetic level.
Link to El Plural
Immunotherapy is gaining ground in the fight against cancer. The tumour has a strategy to evade detection by the immune system, thus allowing it to spread throughout the body. Science has discovered this therapy and is working on overcoming this evasion strategy. In this regard, La República has published an interview with Eduard Batlle, head of the Colorectal Cancer Lab at IRB Barcelona.
Catalunya Press, Revista Genética, among other national and international media, have published articles about a study co-led by Travis H. Stracker, head of the Genomic Instability and Cancer Lab, which has identified a key role for enzymes in DNA replication and sensitivity to chemotherapeutic drugs.
Link to Catalunya Press
Link to Revista Genética
Published in Science Advances, the study shows that the TLK1 and TLK2 enzymes are critical for ensuring the copying of DNA.
Loss of TLK1 and TLK2 results in extensive DNA damage during DNA replication and in cancer cell death.
Depletion of TLK1/2 enhances the effectiveness of some chemotherapeutic agents currently being tested in clinical trials
