Alejo E. Rodriguez-Fraticelli was born in Argentina. He studied at the Colegio Nacional de Buenos Aires. In 2008, he moved to Madrid, where he studied Biochemistry, and he received his PhD in Developmental and Cell Biology at the Universidad Autónoma de Madrid in 2014. He then moved to Boston (USA) to work on cell fate determination in hematopoiesis at Harvard University and Boston Children’s Hospital.
During his postdoctoral fellowship, Alejo worked on developing methods for single cell lineage tracing in the hematopoietic system. His work contributed to a recent modern revision of the paradigm of unperturbed in vivo hematopoiesis, demonstrating the coexistence of multiple lineage hierarchies with imprinted and biased cellular fates.
"Our lab is a playground for scientists from different backgrounds bound together by the common interest of understanding regeneration and its evil twin, cancer"
Since 2015, Alejo has also worked with the lab of Dr. Allon Klein (Harvard Medical School) to combine single cell lineage tracing and single cell sequencing methods.
His works spun out a revolutionary way to connect cellular states with cellular fates through clonal analysis, to determine how cell state variation contributes to cell phenotypic heterogeneity.
In 2021, Alejo has become Group Leader at IRB Barcelona where, he heads the Quantitative Stem Cell Dynamics lab, which he defines as "a playground for scientists from different backgrounds bound together by the common interest of understanding regeneration and its evil twin, cancer".
Their goal is to provide talented individuals with support, resources, flexibility and understanding, to ultimately help them become global scientific leaders. In their lab, exploring is encouraged, challenges are mandatory, and failing is the only way to move forward.
On a personal level, they aim to be a diverse group, with different ethnicities and philosophies, and with a passion for sharing: "If you're weird, here you'll find a home. If you're unique, here you'll find a group of peers. And if you're a bit crazy, here you'll find the opportunities that you need to break out".
Their goal is "to give you the raw materials for you to build something truly game-changing. Here, we play games, we have fun, and we science it out".
About IRB Barcelona
Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence, a seal that was awarded in 2011. The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 27 laboratories and eight core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions. IRB Barcelona is an international centre that hosts 400 employees and more than 30 nationalities. It is located in the Barcelona Science Park. IRB Barcelona is a CERCA center, and a member of the Barcelona Institute of Science and Technology (BIST).