Impact in the media of the study led by Eduard Batlle on the role of the BMP protein as a safety mechanism to restrict colon tumour formation. The article has been published in Nature Cell Biology.
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23 June 2014
The colon has a safety mechanism that restricts tumour formation
An understanding of the molecular basis of differences in the incidence and survival of cancer between men and women may allow the discovery of specific and more effective treatments.
The study, published in Science Advances, compares the brain tumours of male and female flies at the molecular level and identifies proteins responsible for the different degree of aggressiveness.
The radio station COPE, the newspaper ABC, RTVE and the scientific news agency SINC, among other media, have echoed news about a study led by Xavier Salvatella, head of the Molecular Biophysics Laboratory at IRB Barcelona. This study indicates that chaperone protein Hps70 could be an attractive therapeutic target for the treatment of Kennedy’s disease, a rare neuromuscular disorder, as well as castration-resistant prostate cancer.
Activation of the chaperone protein Hsp70 leads to a decrease in the formation of androgen receptor aggregates, which give rise to muscular atrophy in patients with Kennedy´s disease, a rare condition for which no treatment is available.
The results may also be useful in the search for a treatment for castration-resistant prostate cancer, a disease that causes 30,000 death a year in Europe and for which there is no treatment.
The study, which has been published in Nature Communications, is a collaboration with the University of California San Francisco and the University of Michigan.
