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The origin of metastasis, a finding that offers hope

25 Mar 20




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 The EFE Agency has published an interview with  Gloria Pascual, associate researcher in the Stem Cells and Cancer Lab at the Institute for Research in Biomedicine (IRB Barcelona). In the interview she talks about the discovery made by Joan Massagué regarding the origin or metastasis.

The researcher explains that the study demonstrates what has been suspected for years, namely that “the metastatic process is highly influenced by environmental conditions within the tumour encountered by cells and does not depend so much on the acquisition of a specific mutation”.

Pascual adds that the final goal of research into metastasis is the discovery of new therapeutic targets that are specifically directed against the metastatic cell. “Dr. Massagué and his team have identified a protein, L1CAM, that mediates metastasis. This discovery paves the way for the development of new drugs to treat certain kinds of cancer, particularly those that respond to or have high levels of this protein,” she says.


Link to : EFE

About IRB Barcelona

Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence, a seal that was awarded in 2011. The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 27 laboratories and eight core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions. IRB Barcelona is an international centre that hosts 400 employees and more than 30 nationalities. It is located in the Barcelona Science Park. IRB Barcelona is a CERCA center, and a member of the Barcelona Institute of Science and Technology (BIST).