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About
Angel R. Nebreda
Research Group:
Signalling and Cell Cycle Laboratory
Unit:
CANCER SCIENCE
Position:
Group Leader
Office:
EM01B53-4-C53
Telephone:
+34 93 40 31379
Email:
angel.nebreda@irbbarcelona.org
ICREA Research Professor, ERC Advanced Grant
View research group
Selected group publications
Requirement for epithelial p38α in KRAS-driven lung tumor progression
Vitos-Faleato J, Real SM, Gutierrez-Prat N, Villanueva A, Llonch E, Drosten M, Barbacid M and Nebreda AR.
PNAS,
117
(5), 2588-2596 (2020)
Regulation of tumor angiogenesis and mesenchymal-endothelial transition by p38α through TGF-β and JNK signaling
Batlle R, Andrés E, Gonzalez L, Llonch E, Igea A, Gutierrez-Prat N, Berenguer-Llergo A and Nebreda AR.
Nat Commun,
10
(1), 3071 (2019)
Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells
Cánovas B, Igea A, Sartori AA, Gomis RR, Paull TT, Isoda M, Pérez-Montoyo H, Serra V, González-Suárez E, Stracker TH and Nebreda AR.
Cancer Cell,
33
(6), 1094-1110. (2018)
Induction of oxidative metabolism by the p38α/MK2 pathway
Trempolec N, Muñoz JP, Slobodnyuk K, Marin S, Cascante M, Zorzano A and Nebreda AR.
Sci Rep,
7
(1), 11367 (2017)
Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope
Mikolcevic P, Isoda M, Shibuya H, del Barco Barrantes I, Igea A, Suja JA, Shackleton S, Watanabe Y and Nebreda AR.
Nat Commun,
7
11084 (2016)
Gene Dosage Imbalance Contributes to Chromosomal Instability-Induced Tumorigenesis
Clemente-Ruiz M, Murillo-Maldonado JM, Benhra N, Barrio L, Pérez L, Quiroga G, Nebreda AR and Milán M.
Dev Cell,
36
(3), 290-302 (2016)
The Stress Kinase p38α as a Target for Cancer Therapy
Igea A and Nebreda AR.
Cancer Res,
75
(19), 3997-4002 (2015)
Dual function of p38α MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival
Gupta J, del Barco Barrantes I, Igea A, Sakellariou S, Pateras IS, Gorgoulis VG and Nebreda AR.
Cancer Cell,
25
(4), 484-500 (2014)
Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH
Urosevic J, Garcia-Albéniz X, Planet E, Real S, Céspedes MV, Guiu M, Fernandez E, Bellmunt A, Gawrzak S, Pavlovic M, Mangues R, Dolado I, Barriga FM, Nadal C, Kemeny N, Batlle E, Nebreda AR and Gomis RR.
Nat Cell Biol,
16
(7), 685-94 (2014)
Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK
Pereira L, Igea A, Canovas B, Dolado I and Nebreda AR.
EMBO Mol Med,
5
(11), 1759-1774 (2013)
SnapShot: p38 MAPK signaling
Trempolec N, Dave-Coll N and Nebreda AR.
Cell,
152
(3), 656-657 (2013)
SnapShot: p38 MAPK substrates
Trempolec N, Dave-Coll N and Nebreda AR.
Cell,
152
(4), 924-925 (2013)
Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development
del Barco Barrantes I, Coya JM, Maina F, Arthur JS and Nebreda AR.
P Natl Acad Sci Usa,
108
(31), 12764-9 (2011)
Mechanisms and functions of p38 MAPK signalling
Cuadrado A and Nebreda AR.
Biochem J,
429
(3), 403-17 (2010)
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