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Research

At the forefront of biomedicine

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Ignasi Toledano

IRB Barcelona
Unit:
Position:
PhD Student
Office:
CL01C74
Telephone:
+34 93 40 39954
Research Group

Selected group publications

TP53-dependent toxicity of CRISPR/Cas9 cuts is differential across genomic loci and can confound genetic screening
Alvarez, MM; Biayna, J; Supek, F
Nature Communications
13
(1 )
4520 -
(2022)
The impact of rare germline variants on human somatic mutation processes
Vali-Pour M; Lehner B; Supek F
Nature Communications
13
(1 )
3724 -
3724
(2022)
Mutational signatures are markers of drug sensitivity of cancer cells
Levatić J; Salvadores M; Fuster-Tormo F; Supek F
Nature Communications
13
(1 )
2926 -
2926
(2022)
Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells
Biayna J; Garcia-Cao I; Álvarez MM; Salvadores M; Espinosa-Carrasco J; McCullough M; Supek F; Stracker TH
Plos Biology
19
(3 )
e3001176 -
(2021)
DNA mismatch repair promotes APOBEC3-mediated diffuse hypermutation in human cancers
Mas-Ponte D; Supek F
Nature Genetics
52
(9 )
958 -
+
(2020)