This species shows several genetic duplications, which may explain its high plasticity and capacity to adapt to diverse farming conditions.
CSIC has headed this research, which has brought about a considerable advance in the development of genomic and biotechnological tools to achieve more sustainable fish farming.
The findings of the study will be applied in genetic selection and environmental programming in order to improve fish quality and interaction with the microorganisms present in the host environment.
Nostrum Biodiscovery, a spin-off from IRB Barcelona and the BSC-CNS, focuses on computational simulation to design new drugs and biotech molecules for the market.
The Senén Vilaró Prize is given each year by the “Consejo Social” of the UB and the Bosch i Gimpera Foundation to the best innovative company.
Published in the journal Nature Cancer, the study analyses how genetic alterations in tumour cells prevent the correct degradation of the proteins involved in tumour development and growth, thereby leading to abnormal cell behaviour.
A machine-learning model has allowed the scientists to obtain the most extensive annotation of the ubiquitin-mediated protein degradation system.
The analysis proposes a potential new clinical approach for cancer through the inhibition of oncoproteins with impaired degradation systems.
When you hear the word ‘immunotherapy’, the first thing that comes to mind is that it is a highly effective treatment for cancer. But could it also be the solution or hope for other conditions?
This was precisely the subject addressed at the Barcelona Biomed Conference “Immunotherapy beyond cancer. A cure for age-related diseases”, an event organised by the Institute for Research in Biomedicine (IRB Barcelona) from 18 to 20 November that brought together more than 100 scientists.
Over 3 days, researchers from all over the world have emphasized the potential of this new therapy for other applications. In this regard, Manuel Serrano, ICREA...
Organised by PhD students and postdocs, ENABLE is aimed at the community of young researchers working in biomedicine.
The 3rd ENABLE symposium was held in Nijmegen (the Netherlands) from 13 to 15 November.
The symposium was cofunded by the European Commission and is managed and organised by four research institutes (IRB Barcelona, RIMLS, NNF CPR, and SEMM) and a science communication agency (Scienseed).
Scientists at IRB Barcelona determine the genetic alterations in the cells of cancer patients caused by the main cancer therapies.
This is an important step towards understanding the long-term side effects and optimizing treatments against cancer.
The results have been published in the journal Nature Genetics.
The jury unanimously decided to award Salvador Aznar Benitah in acknowledgement of his work on adult stem cells and the relation of these with circadian rhythms and metastasis, and also in recognition of his recent entrepreneurial activity.
The award is given in recognition of biochemistry and molecular biology research of excellence performed mainly in Spain.
In 2017, Fran Supek started his research group at IRB Barcelona devoted to statistical genomics.
Through its Young Investigator Programme, EMBO identifies and supports some of the best young researchers in the life sciences.
The funded project will address the development of metastasis in breast cancer.
The grant, which is specifically for research into breast cancer, has been given by the foundation, in collaboration with Mango.
Fero is a private foundation that promotes translational cancer research in Spain.
Both transcription factors regulate the expression of genes involved in embryo development, among other functions, although they exert very different roles.
The study also refutes the theory accepted to date that SMAD2 does not bind to DNA.
Published in Genes & Development, the research is the result of collaboration between Maria J. Macias’ lab at IRB Barcelona and Joan Massagué’s group at the Sloan Kettering Institute (New York, US).