News

Scientific news
<p>A massive genomic sequencing and assembly strategy has allowed the scientists to gain the most complete vision of the genomic sequence of this species</p>
20 Dec 2019

This species shows several genetic duplications, which may explain its high plasticity and capacity to adapt to diverse farming conditions.

CSIC has headed this research, which has brought about a considerable advance in the development of genomic and biotechnological tools to achieve more sustainable fish farming.

The findings of the study will be applied in genetic selection and environmental programming in order to improve fish quality and interaction with the microorganisms present in the host environment.

Institutional news
<p>Modesto Orozco during the award ceremony</p>
12 Dec 2019

Nostrum Biodiscoverya spin-off from IRB Barcelona and the BSC-CNS, focuses on computational simulation to design new drugs and biotech molecules for the market.

The Senén Vilaró Prize is given each year by the “Consejo Social” of the UB and the Bosch i Gimpera Foundation to the best innovative company.

Scientific news
<p>To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin for degradation. Francisco Martínez, IRB Barcelona.</p>
2 Dec 2019

Published in the journal Nature Cancer, the study analyses how genetic alterations in tumour cells prevent the correct degradation of the proteins involved in tumour development and growth, thereby leading to abnormal cell behaviour.

A machine-learning model has allowed the scientists to obtain the most extensive annotation of the ubiquitin-mediated protein degradation system.

The analysis proposes a potential new clinical approach for cancer through the inhibition of oncoproteins with impaired degradation systems.

Institutional news
<p>Manuel Serrano, ICREA researcher at IRB Barcelona, during his talk at the Barcelona Biomed Conference.</p>
21 Nov 2019

When you hear the word ‘immunotherapy’, the first thing that comes to mind is that it is a highly effective treatment for cancer. But could it also be the solution or hope for other conditions? 

This was precisely the subject addressed at the Barcelona Biomed Conference “Immunotherapy beyond cancer. A cure for age-related diseases”, an event organised by the Institute for Research in Biomedicine (IRB Barcelona) from 18 to 20 November that brought together more than 100 scientists.

Over 3 days, researchers from all over the world have emphasized the potential of this new therapy for other applications. In this regard, Manuel Serrano, ICREA...

Institutional news
<p>ENABLE symposium 2019</p>
19 Nov 2019

Organised by PhD students and postdocs, ENABLE is aimed at the community of young researchers working in biomedicine.

The 3rd ENABLE symposium was held in Nijmegen (the Netherlands) from 13 to 15 November.

The symposium was cofunded by the European Commission and is managed and organised by four research institutes (IRB Barcelona, RIMLS, NNF CPR, and SEMM) and a science communication agency (Scienseed).

Scientific news
<p>Researchers at IRB Barcelona have identified these genetic footprints produced by some cancer treatments and have for the first time been able to calculate the genetic toxicity of some of these treatments. Claudia Arnedo, IRB Barcelona.</p>
19 Nov 2019

Scientists at IRB Barcelona determine the genetic alterations in the cells of cancer patients caused by the main cancer therapies.

This is an important step towards understanding the long-term side effects and optimizing treatments against cancer.

The results have been published in the journal Nature Genetics.

Institutional news
<p>José Picón (Fundación Tatiana Pérez de Guzmán el Bueno-FTPGB), Ángel Carracedo, César Nombela (Fúndación Carmen y Severo Ochoa-FCSO), Salvador Aznar (IRB Barcelona), Rosa Menéndez (CSIC), César de Haro (FCSO) y Alvaro Matud (FTPGB)</p>
14 Nov 2019

The jury unanimously decided to award Salvador Aznar Benitah in acknowledgement of his work on adult stem cells and the relation of these with circadian rhythms and metastasis, and also in recognition of his recent entrepreneurial activity.

The award is given in recognition of biochemistry and molecular biology research of excellence performed mainly in Spain.

Institutional news
<p>Fran Supek, head of the Genome Data Science laboratory at IRB Barcelona</p>
13 Nov 2019

In 2017, Fran Supek started his research group at IRB Barcelona devoted to statistical genomics.

Through its Young Investigator Programme, EMBO identifies and supports some of the best young researchers in the life sciences.

Institutional news
<p>Roger Gomis, head of the Growth Control and Metastasis Laboratory, IRB Barcelona.</p>
12 Nov 2019

The funded project will address the development of metastasis in breast cancer. 

The grant, which is specifically for research into breast cancer, has been given by the foundation, in collaboration with Mango.

Fero is a private foundation that promotes translational cancer research in Spain.

Scientific news
<p>The SMAD2 protein can have two orientations. Green indicates the open configuration that allows DNA binding and red the closed configuration, which is incompatible with such binding. Maria J. Macias, IRB Barcelona.</p>
11 Nov 2019

Both transcription factors regulate the expression of genes involved in embryo development, among other functions, although they exert very different roles.

The study also refutes the theory accepted to date that SMAD2 does not bind to DNA.

Published in Genes & Development, the research is the result of collaboration between Maria J. Macias’ lab at IRB Barcelona and Joan Massagué’s group at the Sloan Kettering Institute (New York, US).