In the media

<p>A invasive front of highly aggressive tumour cells (in green). Confocal microscopy image. Alexandra Avgustinova, IRB Barcelona.</p>
28 Dec 2018 - Hidden Nature

The web Hidden Nature has published an article about the 10 investigations that they considered to be the most important ones published in 2018. One of them refers to epigenetic therapies and mentions research research that supports and rejects them. In this regard, they mention the study led by Salvador Aznar Benitah at IRB Barcelona and published in Nature Cell Biology. The study in question concludes that care must be taken with drugs that inhibit epigenetic factors as they could cause the appearance of aggressive tumours.

Link to Hidden Nature

<p>A invasive front of highly aggressive tumour cells (in green). Confocal microscopy image. Alexandra Avgustinova, IRB Barcelona.</p>
20 Dec 2018 -

The journal Biocentury Innovations has published an article on the study led by IRB Barcelona researchers Salvador Aznar Benitah and Fran Supek and first-authored by postdoctoral researcher Alexandra Avgustinova. The study has shown that increasing chromatin accessibility in cancer promotes tumour aggressiveness and does not reduce tumour mutation burden, as previously believed. The article refers to one of the main conclusions of the study, namely the need to evaluate the long-term effects of chromatin modifiers in tumour models before taking them into the clinic.


<p>Alexandra Avgustinova, postdoctoral fellow at IRB Barcelona</p>
18 Dec 2018 - Medical Research

Medical Research has interviewed Alexandra Avgustinova, postdoctoral fellow at IRB Barcelona, about a study published as first author in the journal Nature Cell Biology. In the interview she explains that they have demonstrated that the common belief that chromatin opening is one of the determinants of a number of DNA mutations is incorrect. This discovery, says Avgustinova, is important for the fields of oncology and cancer genomics. “We were surprised to see that this observation was interpreted as a causal association, as it was, to a great extent, based on correlative studies without any experimental support. We decided to experimentally test for the first time whether the alteration...

<p>Gabby Silberman, general director of the Barcelona Institute of Science and Technology (BIST)</p>
13 Dec 2018 - La Vanguardia

La Vanguardia newspaper has published an opinion article by Gabby Silberman, general director of the Barcelona Institute of Science and Technology (BIST), an organisation of which IRB Barcelona is a member. It is urgent for the government to increase public allocations for science to reach the European average of investment in R+D, 2.07% of GDP in 2017, compared to a low 1.2% in Spain. Silberman also emphasizes the great value that doctorate people have in science for society and how BIST centers look after them to train them during their doctorate and postdoctoral studies with a wide range of abilities. "We are redirecting our postdoctoral training programmes, because we are sure that...

<p>Antonio Zorzano, head of the Complex Metabolic Diseases and Mitochondria Lab</p>
11 Dec 2018 - El Pais

The newspaper El País has published an article on the pros and cons of intermittent fasting. The article refers to two kinds of fasting, namely the 5:2 fast, on which you can eat with no calorie restriction for five days and on the other two days no solids are allowed, and the 18:6 fast, which proposes that all the meals of the day are eaten within 6 hours, while the remaining 18 are devoted to fasting. The article includes the opinion of IRB Barcelona researcher Antonio Zorzano, who says, "I have still not seen this reflected in studies, but we must err on the side of caution before telling  people that they can do these diets ", and goes on to conclude that people on such diets should...

<p>Teresa Tarragó. Image: El Periódico</p>
7 Dec 2018 -

Expansión, El Periódico de Catalunya and Diario de Córdoba, among other media, have published articles about the biotechnologist Iproteos, a company created in 2011 by the scientists Teresa Tarragó and Ernest Giralt and based on the transfer of a technology developed atIRB Barcelona and the University of Barcelona (UB). The company has launched a project to develop a therapeutic strategy, designed by IBEC, to treat solid tumours, which account for 90-95% of cancer cases.

Link to El Periódico de Catalunya...

<p>Image: SINC</p>

SINC, El Público, Catalunya Vanguardista and the newspaper Heraldo de Aragón, have published an article about the process and conditions that triggers cancer according to a study published in the journal Science that raises new theories about aging. The article includes the opinion of Salvador Aznar Benitah, ICREA researcher at IRB Barcelona, about the study: "it is a very well done piece of work, with a very sophisticated analysis. We tend to think that the tumour tissue has mutations and the healthy one does not, but that is not the case. Healthy tissue can accumulate changes and appear normal, but it is no longer a normal tissue. "

Link to...

<p>Image: IRB Barcelona</p>

La Vanguardia, Cope, Revista Genética, among other media, have each published an article about the latest study led by ICREA researchers Salvador Aznar Benitah and Fran Supek. The study warns that special care should be taken regarding epigenetic therapies since although their anti-tumour effect may be beneficial initially, they can trigger the development of more aggressive tumours later on.

Link to La Vanguardia

Link to...

<p>Manuel Serrano, group leader of the Cellular Plasticity and Disease laboratory</p>
19 Nov 2018 - LA RAZÓN & OTHER MEDIA

La Razón and Info Diabético have each published an article about the work done by Manuel Serrano at IRB Barcelona: "If we eliminate damaged cells, the function of aged tissues is greatly improved, that is, they are rejuvenated," says Serrano, who goes on to point out that "it has been possible to delay and reverse the aging of small mammals, such as mice, with the use of experimental drugs that eliminate damaged cells."

Link to La Razón

Link to...

<p>Source: Nació Digital</p>
16 Nov 2018 - La Nació

Nació Digital has published an article about "Vi per Vida", an initiative promoted by the sommelier Xavier Ayala that aims to raise funds to support cancer research and metastasis at IRB Barcelona. The event will take place in Sant Sadurní d’Anoia on Sunday 2 December.

Link to Nacio Digital