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Development and Growth Control Laboratory News

Media mentions
MedicalXpress - Some tumors eliminate healthy neighboring cells to grow, study reveals
Scientific
Study in flies reveals how some tumours eliminate healthy neighbouring cells to grow
Media mentions
MedicalXpress - Mitochondria identified as key players in a rare disease causing microcephaly
Scientific
Mitochondria identified as key player in a rare disease causing microcephaly
Scientific
New tool to generate aneuploidies and analyse their impact on development
Institutional
World Cancer Day 2024: Highlights of IRB Barcelona’s cancer research
Scientific
Chromosomal instability in cancer cells causes DNA damage and promotes invasiveness
Institutional
IRB Barcelona to host five students from the Barcelona International Youth Science Challenge
Institutional
Dr. Marco Milán, elected new EMBO member
Media mentions
Investigadors de l'IRB descobreixen un mecanisme utilitzat pels insectes en la regeneració de les ales - La Vanguardia
Scientific
A genomic region that is exclusively dedicated to the formation and regeneration of a single organ
Scientific
Relationship between chromosomal instability and senescence revealed in the fly Drosophila
Drosophila's brain exhibiting the ring gland, the equivalent to the human's prothoracic gland, responsible for steroidal hormone production.
Scientific
Discovery of a mechanism by which epithelial tumours cause developmental delays
Scientific
Deciphering the mechanism that determines organ size and shape
Carme Cortina, researcher at IRB Barcelona
Media mentions
Five days at the Barcelona Science Park
p53 target genes (green) are upregulated in undergrowing cell populations (magenta).
Scientific
In perfect shape: how cells maintain organ proportions
Proliferative and invasive capacity of tumour cells (centre) compared to normal cells (left) and effect of TRAMETINIB treatment, which reduces the invasive capacity and tumoural load (right). Marco Milán, IRB Barcelona.
Media mentions
Advancing in the battle against cancer
Proliferative and invasive capacity of tumour cells (centre) compared to normal cells (left) and effect of TRAMETINIB treatment, which reduces the invasive capacity and tumoural load (right). Marco Milán, IRB Barcelona.
Scientific
Researchers at IRB Barcelona manage to selectively eliminate cells that express the oncogene RAS, which is present in 30% of human cancers
Biennal Ciutat i Ciència
Outreach
IRB Barcelona to participate in the first Biennal Ciutat i Ciència event
Drosophila epithelium subjected to chromosomal instability (CIN): cells start invading the neighbouring tissues. Magenta labels the nuclei of all the epithelium while green labels the membranes of cells subjected to CIN (L Barrio, IRB Barcelona)
Media mentions
Scientists show that the chromosomal instability of tumours promotes metastasis
Drosophila epithelium subjected to chromosomal instability (CIN): cells start invading the neighbouring tissues. Magenta labels the nuclei of all the epithelium while green labels the membranes of cells subjected to CIN (L Barrio, IRB Barcelona)
Scientific
A study using Drosophila sheds light on the metastatic behaviour of human tumours
Innovation
Chromosomal instability in tumours revealed to promote metastasis
Image: La Pedrera
Institutional
The Barcelona International Youth Science Challenge (BIYSC) will bring together students from the 5 continents
Joan Massagué, director of the Sloan Kettering Institute of New York. Image: Jordi Casañas (Mahala, IRB Barcelona)
Institutional
Joan Massagué calls on society to get on board with the challenge posed by metastasis
Colon cancer stem cells, in green (G. Turon, IRB Barcelona)
Institutional
Cancer metastases slowly unveil their weaknesses
Media mentions
Award goes to scientist who practices equality
In this mouse embryo structures can be observed that contain neurofilament, stained cyan, and E-Cadherin, in magenta, showing, respectively, the nervous system and internal organs (Authors: Jim Swoger, Jürgen Mayer, Laura Quintana. CRG 2017)
Institutional
Embryonic development inspires regenerative medicine
Media mentions
Scientists turn to embryos in search of a way to build new organs
Tumour (red) covered by collagen (green), which is being deposited by cells of the immune system (cyan). (Image: Mariana Muzzopappa, IRB Barcelona)
Media mentions
Cell growth of epithelial tumours identified
Tumour (red) covered by collagen (green), which is being deposited by cells of the immune system (cyan). (Image: Mariana Muzzopappa, IRB Barcelona)
Scientific
Internal mechanism found to be responsible for the limitless growth potential of epithelial tumours