Alessandro Ruffoni

Position:

Alumni -

Posdoctoral Fellow

Office:

cluster-EM01B11

Telephone:

+34 93 40 37096

Email:

alessandro.ruffoni@irbbarcelona.org

Left IRB Barcelona in February 2017

Research Group

Laboratory of Molecular Biophysics

Mechanisms of Disease

Selected group publications

A MEC-2/stomatin condensate liquid-to-solid phase transition controls neuronal mechanotransduction during touch sensing

Sanfeliu-Cerdán N, Català-Castro F, Mateos B, Garcia-Cabau C, Ribera M, Ruider I, Porta-de-la-Riva M, Canals-Calderón A, Wieser S, Salvatella X, Krieg M

Nature Cell Biology

(2023)

Aberrant phase separation and nucleolar dysfunction in rare genetic diseases

Mensah MA, Niskanen H, Magalhaes AP, Basu S, Kircher M, Sczakiel HL, Reiter AMV, Elsner J, Meinecke P, Biskup S, Chung BHY, Dombrowsky G, Eckmann-Scholz C, Hitz MP, Hoischen A, Holterhus PM, Hülsemann W, Kahrizi K, Kalscheuer VM, Kan A, Krumbiegel M, Kurth I, Leubner J, Longardt AC, Moritz JD, Najmabadi H, Skipalova K, Snijders Blok L, Tzschach A, Wiedersberg E, Zenker M, Garcia-Cabau C, Buschow R, Salvatella X, Kraushar ML, Mundlos S, Caliebe A, Spielmann M, Horn D, Hnisz D

Nature

614

(7948 )

564 -

(2023)

A glutamine-based single α-helix scaffold to target globular proteins

Escobedo A, Piccirillo J, Aranda J, Diercks T, Mateos B, Garcia-Cabau C, Sánchez-Navarro M, Topal B, Biesaga M, Staby L, Kragelund BB, García J, Millet O, Orozco M, Coles M, Crehuet R, Salvatella X

Nature Communications

(1 )

7073 -

(2022)

Small molecules targeting the disordered transactivation domain of the androgen receptor induce the formation of collapsed helical states

Zhu, JQ; Salvatella, X; Robustelli, P

Nature Communications

(1 )

6390 -

(2022)

Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation

Gonzalez-Arzola, K; Diaz-Quintana, A; Bernardo-Garcia, N; Martinez-Fabregas, J; Rivero-Rodriguez, F; Casado-Combreras, MA; Elena-Real, CA; Velazquez-Cruz, A; Gil-Caballero, S; Velazquez-Campoy, A; Szulc, E; Gavilan, MP; Ayala, I; Arranz, R; Rios, RM; Salvatella, X; Valpuesta, JM; Hermoso, JA; De la Rosa, MA; Diaz-Moreno, I

Nature Structural & Molecular Biology

(10 )

1024 -

(2022)