Chemistry and Molecular PharmacologyLaboratory of Molecular Biophysics
ICREA Research Professor, ERC Consolidator Grant
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Xavier Salvatella: "Magical Choreography"A high resolution description of the structure and dynamics of proteins is a very useful tool to study the properties and the function of these important biomacromolecules and, most importantly, to understand how changes in sequence or environment can lead to disease. The research work carried out at the Laboratory of Molecular Biophysics aims, on the one hand, at developing methods to probe the fluctuations of the structure of proteins by combining experimental data and molecular simulations and, on the other hand, at understanding how changes in such motions relate to the molecular recognition of proteins, to their function and disease.
This group is financially supported by the following:
- Ministerio de Economía y Competitividad (MINECO)
- European Commission (EC), Fondo Europeo de Desarrollo Regional (FEDER), "Una manera de hacer Europa"
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Group news & mentions
Group news & mentions
Liquid-like droplets are highly dynamic cytoplasmic aggregates of proteins with no apparent structure.
Prostate cancer, Alzheimer’s, Parkinson’s...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional st
Knowledge of the minute details of the proteins that are linked to diseases is crucial if we are to discover therapeutic targets and thus pave the way for possible treatments.
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