Mechanisms of Disease Laboratory of Molecular Biophysics
A high resolution description of the structure and dynamics of proteins is a very useful tool to study the properties and the function of these important biomacromolecules and, most importantly, to understand how changes in sequence or environment can lead to disease. The research work carried out at the Laboratory of Molecular Biophysics aims, on the one hand, at developing methods to probe the fluctuations of the structure of proteins by combining experimental data and molecular simulations and, on the other hand, at understanding how changes in such motions relate to the molecular recognition of proteins, to their function and disease.
This group is financially supported by the following:
- Ministerio de Economía y Competitividad (MINECO)
- European Commission (EC), Fondo Europeo de Desarrollo Regional (FEDER), "Una manera de hacer Europa"
Group news & mentions
A posible therapeutic target for Kennedy’s disease and prostate cancer
Researchers at IRB Barcelona identify a possible therapeutic target for Kennedy´s disease and prostate cancer
Researchers at IRB Barcelona discover the structural consequences of the mutation that causes Kennedy disease
Researchers identify a molecule that halts and reverses neurodegeneration in Parkinson’s disease
09MarBiostatistics / Bioinformatics Unit: Get started on Statistical Concepts, Experimental Design and Exploratory Tools
10MarSpatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution [IRB Research Nodes Seminar]
12MarImprovement of the efficacy and persistence of academic CAR-T cells for the treatment of mature-B cell malignancies