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Research

At the forefront of biomedicine

Ignacio Miguel Martínez De Lejarza

Unit:
Position:
Alumni - PhD Student
Office:
EMPBC52-53
Telephone:
+34 93 40 31197
Left IRB Barcelona in February 2022
Research Group

Selected group publications

Human tRNAs with inosine 34 are essential to efficiently translate eukarya-specific low-complexity proteins
Torres, AG; Rodríguez-Escribà, M; Marcet-Houben, M; Vieira, HGS; Camacho, N; Catena, H; Recio, MM; Rafels-Ybern, A; Reina, O; Torres, FM; Pardo-Saganta, A; Gabaldón, T; Novoa, EM; de Pouplana, LR
Nucleic Acids Research,
49
(12 )
7011
- 7034
(2021)
The mitochondrial tRNA conundrum
de Pouplana, LR
Nature Reviews Molecular Cell Biology,
21
(7 )
361
- 361
(2020)
The Expansion of Inosine at the Wobble Position of tRNAs, and Its Role in the Evolution of Proteomes
Rafels-Ybern, A; Torres, AG; Camacho, N; Herencia-Ropero, A; Frigolé, HR; Wulff, TF; Raboteg, M; Bordons, A; Grau-Bove, X; Ruiz-Trillo, I; de Pouplana, LR
Molecular Biology And Evolution,
36
(4 )
650
- 662
(2019)
Differential expression of human tRNA genes drives the abundance of tRNA-derived fragments
Torres, AG; Reina, O; Attolini, CSO; de Pouplana, LR
Proceedings Of The National Academy Of Sciences Of The United States Of America,
116
(17 )
8451
- 8456
(2019)
Mitochondrial Protein Synthesis and mtDNA Levels Coordinated through an Aminoacyl-tRNA Synthetase Subunit
Picchioni, D; Antolin-Fontes, A; Camacho, N; Schmitz, C; Pons-Pons, A; Rodríguez-Escribà, M; Machallekidou, A; Güler, MN; Siatra, P; Carretero-Junquera, M; Serrano, A; Hovde, SL; Knobel, PA; Novoa, EM; Solà-Vilarrubias, M; Kaguni, LS; Stracker, TH; de Pouplana, LR
Cell Reports,
27
(1 )
40
(2019)
Saturation of recognition elements blocks evolution of new tRNA identities
Saint-Léger, A; Bello, C; Dans, PD; Torres, AG; Novoa, EM; Camacho, N; Orozco, M; Kondrashov, FA; de Pouplana, LR
Science Advances,
2
(4 )
e1501860
(2016)
Inosine modifications in human tRNAs are incorporated at the precursor tRNA level
Torres, AG; Piñeyro, D; Rodríguez-Escribà, M; Camacho, N; Reina, O; Saint-Léger, A; Filonava, L; Batlle, E; de Pouplana, LR
Nucleic Acids Research,
43
(10 )
5145
- 5157
(2015)
Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo
Novoa, EM; Camacho, N; Tor, A; Wilkinson, B; Moss, S; Marín-García, P; Azcárate, IG; Bautista, JM; Mirando, AC; Francklyn, CS; Varon, S; Royo, M; Cortés, A; de Pouplana, LR
Proceedings Of The National Academy Of Sciences Of The United States Of America,
111
(51 )
E5508
- E5517
(2014)
Human mitochondrial disease-like symptoms caused by a reduced tRNA aminoacylation activity in flies
Guitart, T; Picchioni, D; Pineyro, D; de Pouplana, LR
Nucleic Acids Research,
41
(13 )
6595
- 6608
(2013)