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Research

At the forefront of biomedicine

Dr. Jake Ward

Jake Ward
Unit:
Position:
Postdoctoral Fellow
Office:
EM01B24
Telephone:
+34 93 40 37123
Research Group

Selected group publications

Biophysical and computational approaches to study ternary complexes: A 'cooperative relationship' to rationalize targeted protein degradation
Ward JA, Perez-Lopez C, Mayor-Ruiz C
Chembiochem
24
(10 )
e202300163 -
e202300163
(2023)
Molecular glue degraders: From serendipity to hunting and design
Nieto-Barrado L; Domostegui A; Mayor-Ruiz C
In: Inducing Targeted Protein Degradation: From Chemical Biology To Drug Discovery And Clinical Applications. Ed: Wiley-Vch.
Chapter 6
177 -
204
(2022)
Chasing molecular glue degraders: screening approaches
Domostegui A, Nieto-Barrado L, Perez-Lopez C, Mayor-Ruiz C
Chemical Society Reviews
51
(13 )
5498 -
5517
(2022)
Identification and selectivity profiling of small-molecule degraders via multi-omics approaches
Scholes NS; Mayor-Ruiz C; Winter GE
Cell Chemical Biology
28
(7 )
1048 -
1060
(2021)
Rational discovery of molecular glue degraders via scalable chemical profiling
Mayor-Ruiz, C., Bauer, S., Brand, M., Kozicka, Z., Siklos, M., Imrichova, H., Kaltheuner, I., Hahn, E., Seiler, K., Koren, A., Petzold, G., Fellner, M., Bock, C., Mueller, A.C., Zuber, J., Geyer, M., Thomä, N.H., Kubicek, S., Winter, G.E
Nat Chem Bio
(2020)