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Research

At the forefront of biomedicine

Dr. Jesús García

Unit:
Position:
Senior Research Officer
Office:
EMPBC31-2-4
Telephone:
+34 93 40 20460
Research Group

Selected group publications

Aberrant phase separation and nucleolar dysfunction in rare genetic diseases
Mensah MA, Niskanen H, Magalhaes AP, Basu S, Kircher M, Sczakiel HL, Reiter AMV, Elsner J, Meinecke P, Biskup S, Chung BHY, Dombrowsky G, Eckmann-Scholz C, Hitz MP, Hoischen A, Holterhus PM, Hülsemann W, Kahrizi K, Kalscheuer VM, Kan A, Krumbiegel M, Kurth I, Leubner J, Longardt AC, Moritz JD, Najmabadi H, Skipalova K, Snijders Blok L, Tzschach A, Wiedersberg E, Zenker M, Garcia-Cabau C, Buschow R, Salvatella X, Kraushar ML, Mundlos S, Caliebe A, Spielmann M, Horn D, Hnisz D
Nature
614
(7948 )
564 -
+
(2023)
A glutamine-based single α-helix scaffold to target globular proteins
Escobedo A, Piccirillo J, Aranda J, Diercks T, Mateos B, Garcia-Cabau C, Sánchez-Navarro M, Topal B, Biesaga M, Staby L, Kragelund BB, García J, Millet O, Orozco M, Coles M, Crehuet R, Salvatella X
Nature Communications
13
(1 )
7073 -
(2022)
Small molecules targeting the disordered transactivation domain of the androgen receptor induce the formation of collapsed helical states
Zhu, JQ; Salvatella, X; Robustelli, P
Nature Communications
13
(1 )
6390 -
(2022)
Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation
Gonzalez-Arzola, K; Diaz-Quintana, A; Bernardo-Garcia, N; Martinez-Fabregas, J; Rivero-Rodriguez, F; Casado-Combreras, MA; Elena-Real, CA; Velazquez-Cruz, A; Gil-Caballero, S; Velazquez-Campoy, A; Szulc, E; Gavilan, MP; Ayala, I; Arranz, R; Rios, RM; Salvatella, X; Valpuesta, JM; Hermoso, JA; De la Rosa, MA; Diaz-Moreno, I
Nature Structural & Molecular Biology
29
(10 )
1024 -
+
(2022)
Intrinsically disordered proteins and biomolecular condensates as drug targets
Biesaga M; Frigolé-Vivas M; Salvatella X
Current Opinion In Chemical Biology
62
( )
90 -
100
(2021)