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Research

At the forefront of biomedicine

Philipp Putze

Unit:
Position:
Alumni - MSc Student BIST
Office:
EMPBA22A24
Telephone:
+34 93 40 37018
Left IRB Barcelona in October 2024
Research Group

Selected group publications

scKINETICS: inference of regulatory velocity with single-cell transcriptomics data
Burdziak, C; Zhao, CJ; Haviv, D; Alonso-Curbelo, D; Lowe, SW; Pe'er, D
Bioinformatics,
39
(39 Suppl 1 )
i394
- i403
(2023)
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis
Burdziak, C; Alonso-Curbelo, D; Walle, T; Reyes, J; Barriga, F; Haviv, D; Xie, YB; Zhao, Z; Zhao, CJ; Chen, HA; Chaudhary, O; Masilionis, I; Choo, ZN; Gao, V; Luan, W; Wuest, A; Ho, YJ; Wei, YH; Quail, DF; Koche, R; Mazutis, L; Chaligné, R; Nawy, T; Lowe, SW; Pe'er, D
Science,
380
(6645 )
597
(2023)
A gene–environment-induced epigenetic program initiates tumorigenesis
Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.
Nature,
(2021)
Senolytic CAR T cells reverse senescence-associated pathologies
Amor C*, Feucht J*, Leibold J*, Ho Y-J, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, et al, Sadelain M, Lowe SW.
(*) these authors contributed equally
Nature,
(2020)
An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants
Paz Zafra M, Parsons MJ, Kim J, Alonso-Curbelo D, Goswami S, Schatoff EM, Han T, Katti A, Calvo Fernandez MT, Wilkinson JE, Piskounova E and Dow LE.
Cancer Discovery ,
(2020)
Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancer
Osmanbeyoglu HU, Shimizu F*, Rynne-Vidal A*, Alonso-Curbelo D*, Chen HA, Wen HY, Yeung TL, Jelinic P, Razavi P, Lowe SW, Mok SC, Chiosis G, Levine DA, Leslie CS.
(*) these authors contributed equally
Nature Communications ,
(2019)
Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity
Finley LWS*, Vardhana SA*, Carey BW*, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, et al, [corr author] Thompson CB.
(*) these authors contributed equally
Nature Cell Biology ,
(2018)
Arid1a restrains Kras-dependent changes in acinar cell identity
Livshits D, Alonso-Curbelo D, Morris JP4th, Koche R, Saborowski M, Wilkinson JE, Lowe SW
eLife,
(2018)
BRD4 connects super enhancer remodeling to senescence immune surveillance
Tasdemir N*, Banito B*, Roe JS*, Alonso-Curbelo D*, Camiolo M, Tschaharganeh DF, Huang CH, Aksoy O, Bolden JE, Chen CC, Fennell M, Thapar V, Chicas A, Vakoc CV, Lowe SW.
(*) these authors contributed equally
Cancer Discovery ,
(2016)