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Rafael Lema

Rafael Lema
Unit:
Position:
Alumni -
Postdoctoral Fellow
Office:
CL01C61-62
Telephone:
+34 93 40 20228
Left IRB Barcelona in December 2020
Research Group

Selected group publications

Impact of DNA methylation on 3D genome structure
Buitrago D; Labrador M; Arcon JP; Lema R; Flores O; Esteve-Codina A; Blanc J; Villegas N; Bellido D; Gut M; Dans PD; Heath SC; Gut IG; Brun Heath I; Orozco M
Nature Communications
12
(1 )
3243 -
(2021)
A multi-modal coarse grained model of DNA flexibility mappable to the atomistic level
Walther J; Dans PD; Balaceanu A; Hospital A; Bayarri G; Orozco M
Nucleic Acids Research
48
(5 )
e29 -
(2020)
An artificial DNAzyme RNA ligase shows a reaction mechanism resembling that of cellular polymerases
Aranda J; Terrazas M; Gómez H; Villegas N; Orozco M
Nature Catalysis
2
(6 )
544 -
552
(2019)
The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry
Terrazas M; Genna V; Portella G; Villegas N; Sánchez D; Arnan C; Pulido-Quetglas C; Johnson R; Guigó R; Brun-Heath I; Aviñó A; Eritja R; Orozco M
Chem
5
(6 )
1619 -
1631
(2019)
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope
Orellana L; Thorne AH; Lema R; Gustavsson J; Parisian AD; Hospital A; Cordeiro TN; Bernadó P; Scott AM; Brun-Heath I; Lindahl E; Cavenee WK; Furnari FB; Orozco M
Proceedings Of The National Academy Of Sciences Of The United States Of America
116
(20 )
10009 -
10018
(2019)