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Highlighting IRB Barcelona's impact on society

Metabolic Engineering and Diabetes Therapy News

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Guinovart: "Advances comparable to the discovery of insulin will be achieved"
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Don't trust your memory
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Neurons need glycogen but in excess this polysaccharide is deadly
Neurons accumulate glycogen in small amounts, which is beneficial for them. Glycogen synthase (in green) and glycogen accumulation in red (Author: Isabel Sáez, IRB)
Scientific
Researchers reveal the dual role of brain glycogen
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Glycogen accumulation in neurons causes damage
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IRB Barcelona demonstrates the harmful effect of glycogen accumulation in neurons
Comparative microscope images. The lower picture shows a cerebellum sample from a healthy mouse. Above, the same tissue after glycogen accumulation. (Jordi Duran. IRB Barcelona)
Scientific
Glycogen accumulation in neurons causes brain damage and shortens the lives of flies and mice
Media mentions
The Good, the Bad and the Ugly
Interneuron obtained from an engineered mouse lacking the malin gene (in green) and showing the accumulation of Lafora bodies (in red).
Scientific
A mouse model brings new perspectives on Lafora disease
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Joan J Guinovart talks about the current situation of science in Spain
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Joan Guinovart: "The worlds of science and sport have many similarities"
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Joan J Guinovart: "The creation, attraction and retention of talent are crucial for success"
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A fatal form of myoclonic epilepsy
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Scientists design a tool to study and induce apoptosis
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Scientists and the knowledge economy
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Public-Private Partnerships: a recipe for success?
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Video-perfil de Joan J. Guinovart a Global Talent
Joan J. Guinovart
Institutional
Joan J. Guinovart winner of the Prat de la Riba Prize, awarded by the "Institut d'Estudis Catalans"
Image obtained by confocal microscopy. The accumulation of glycogen (yellow and red) in neurons caused their degradation and cell suicide ensues. (c)IRB Barcelona
Scientific
The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases
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BioBarça
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La revolución urgente
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Institutional
The Institute for Research in Biomedicine reloaded