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Proliferative and invasive capacity of tumour cells (centre) compared to normal cells (left) and effect of TRAMETINIB treatment, which reduces the invasive capacity and tumoural load (right). Marco Milán, IRB Barcelona.
Scientific
Researchers at IRB Barcelona manage to selectively eliminate cells that express the oncogene RAS, which is present in 30% of human cancers
The DNAzyme 9DB1, whose catalytically active structure and reaction mechanism was unknown, makes use of a mechanism involving two ions, similar to that used by natural enzymes (J. Aranda, IRB Barcelona).
Scientific
A study from IRB Barcelona describes the reaction mechanism of DNAzymes and opens new propsects in the field of biocatalysers
Scientific - Published in Chem
A study makes a significant contribution to progress in gene therapy efficiency by identifying the source of asymmetry in RNA · DNA hybrids
The androgen receptor helix of polyglutamine becomes increasingly stable as the number (n) of glutamine amino acid residues increases.
Scientific
Researchers at IRB Barcelona discover the structural consequences of the mutation that causes Kennedy disease
Innovation
#WeAreIRB: “The Drug Discovery Journey” by Israel Ramos, IRB Barcelona Technology Transfer Consultant
Illustrated view of the different conformations adopted by a flexible small molecule. Colours represent different ensembles of conformations.
Scientific
Molecular dynamics simulation provides a “single-interaction” perspective to protein dynamics and drug binding
Cross section of healthy efferent ducts photographed with a fluorescent microscope
Scientific
Research at IRB Barcelona Sheds Light on the Causes of Male Infertility
Valentina Maria Zinna, Salvador Aznar Benitah, Patrick Welz and Inés Marín Guillén, IRB Barcelona.
Scientific
The body responds to variations in light between the day and night independently of the brain
Institutional
The BSC-IRB Barcelona researcher Toni Gabaldón, vice president of the new Young Academy of Spain

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