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Signalling and Cell Cycle Laboratory News

Scientific
A new inactive form of p38a protein discovered
Scientific
Development of new p38 protein inhibitors with therapeutic potential for some heart diseases
Institutional
Goal: tackling resistance to chemotherapy in triple-negative breast cancer
Institutional
The Spanish Association Against Cancer backs IRB Barcelona research with more than €3M
Scientific
To die or not to die in response to stress, a decision regulated by MK2 protein levels
Begoña Cánovas, postdoctoral fellow at IRB Barcelona's Signalling and Cell Cycle Laboratory
Community
Begoña Cánovas, first author of a review in Nature Reviews Molecular Cell Biology
ICREA researcher at IRB Barcelona, Ángel Nebreda
Media mentions
Inhibition of the protein p38 reduces lung tumour growth
Lung tumor stained for proliferating cells (brown) (IRB Barcelona)
Scientific
Inhibition of p38 reduces the growth of lung tumours
Structure of a blood vessel. Raquel Batlle, IRB Barcelona.
Media mentions
The p38 protein regulates the development of new blood vessels in tumours
Structure of a blood vessel. Raquel Batlle, IRB Barcelona.
Scientific
A study demonstrates that p38 protein regulates the formation of new blood vessels in tumours
Different localization of the proteins involved in apoptosis in basal (Ctrl) and upon death receptor induction with TRAIL. Saška Ivanova, IRB Barcelona
Scientific
Researchers identify a new biomarker for personalised treatments against cancer
Angel R. Nebreda, head of the Signalling and Cell Cycle Laboratory at IRB Barcelona
Media mentions
Discovering therapies that do not cause resistance, one of the challenges of cancer research
Begoña Cánovas, postdoctoral researcher at IRB Barcelona. Source: Alma, Obra Social ”la Caixa”
Media mentions
An unstoppable talent
Angel R. Nebreda, head of the Signalling and Cell Cycle Laboratory at IRB Barcelona
Media mentions
"There have been spectacular advances in many types of tumors"
The AECC ceremony was held in Madrid yesterday, 25th September, the World Cancer Research Day
Institutional
The Spanish Association Against Cancer awards funding to five projects at IRB Barcelona
Media mentions
Breast cancer under scrutiny
Eduard Batlle, head of the Colorectal Cancer laboratory at IRB Barcelona
Institutional
Two ERC Proof of Concept grants to tackle colon cancer and cardiotoxicity
Activated macrophage isolated from mouse intestine. Macrophage marker is shown in green, inflammation marker (iNOS) in red, and nucleus in blue. Author: Catrin Youssif, IRB Barcelona
Media mentions
A study identifies a new mechanism that contributes to the development of colon cancer
Intestine of a patient with ulcerative colitis, a chronic inflammatory disease of the intestine. Macrophage marker is shown in green, activated p38 protein in red, and nucleus in blue. Author: Catrin Youssif, IRB Barcelona
Scientific
A study points to new therapeutic targets for tumours associated with chronic inflammation
Outreach
IRB Barcelona to participate in the 12th “Festival de la Ciència”
Group Leader Angel R. Nebreda and PhD student Begoña Cánovas at the Signalling and Cell Cycle Laboratory (M. Minocri, IRB Barcelona)
Media mentions
Interviews with Begoña Cánovas, postdoc with the Signalling and Cell Cycle laboratory at IRB Barcelona
Image of breast cancer cells derived from a mouse mammary tumour (in blue: nucleus, in green: tubulin) Author: Begoña Cánovas, IRB Barcelona
Media mentions
p38 protein, the saviour of breast cancer cells 'in extremis'
Image of breast cancer cells derived from a mouse mammary tumour (in blue: nucleus, in green: tubulin) Author: Begoña Cánovas, IRB Barcelona
Innovation
Tumour cells evade death through in extremis DNA repair
The image shows interactions between the androgen receptor protein (AR) and the TFIIF protein in red. (Author: Paula Martínez-Cristóbal)
Scientific
Closing in on advanced prostate cancer
Innovation
Three innovation projects at IRB Barcelona are granted funding for market development
Science Festival 2016, Parc de la Ciutadella.
Institutional
Science Festival 2017: A weekend for science in Barcelona
Researchers revealed details of the p38 activation mechanism. The image represents the structural changes from the inactive state (purple) to the active one (green) proposed by X-ray crystallography. Image: Antonija Kuzmanic.
Scientific
Computational research details the activation mechanism of a protein involved in many diseases
Image: IDIBELL.
Media mentions
"Chemoresistance in breast cancer is related to varying tumour cell populations"
Media mentions
Researchers reveal details of the p38α activation mechanism
Angel R. Nebreda.
Media mentions
Angel R. Nebreda: “Scientific research demands a lot of curiosity, you have to be interested in the unknown”