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Research

At the forefront of biomedicine

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Research publications

IntOGen-mutations identifies cancer drivers across tumor types
Gonzalez-Perez, Abel; Perez-Llamas, Christian; Deu-Pons, Jordi; Tamborero, David; Schroeder, Michael P; Jene-Sanz, Alba; Santos, Alberto; Lopez-Bigas, Nuria
10
11
1081 -
1082
2013
Stereodivergent S(N)2@P Reactions of Borane Oxazaphospholidines: Experimental and Theoretical Studies
Zijlstra, Hester; Leon, Thierry; de Cozar, Abel; Guerra, Celia Fonseca; Byrom, Daniel; Riera, Antoni; Verdaguer, Xavier; Bickelhaupt, F Matthias
135
11
4483 -
4491
2013
Dependency of Colorectal Cancer on a TGF-beta-Driven Program in Stromal Cells for Metastasis Initiation
Calon, Alexandre; Espinet, Elisa; Palomo-Ponce, Sergio; Tauriello, Daniele V F; Iglesias, Mar; Virtudes Cespedes, Maria; Sevillano, Marta; Nadal, Cristina; Jung, Peter; Zhang, Xiang H -F; Byrom, Daniel; Riera, Antoni; Rossell, David; Mangues, Ramon; Massague, Joan; Sancho, Elena; Batlle, Eduard
22
5
571 -
584
2012
Reprogramming cell shape with laser nano-patterning
Vignaud T; Galland R; Tseng Q; Blanchoin L; Colombelli J; Théry M
125
9
2134 -
2140
2012
htSeqTools: High-throughput sequencing quality control, processing and visualization in R
Planet E; Attolini C; Reina O; Flores O; Rossell D
28
4
589 -
590
2012
Pten positively regulates brown adipose function, energy expenditure, and longevity
Muñoz Martin, Maria Angeles; Ortega-Molina, Ana; Efeyan, Alejo; Lopez-Guadamillas, Elena; Munoz-Martin, Maribel; Gomez-Lopez, Gonzalo; Canamero, Marta; Mulero, Francisca; Pastor, Joaquin; Martinez, Sonia; Romanos, Eduardo; Mar Gonzalez-Barroso, M; Rial, Eduardo; Valverde, Angela M; Bischoff, James R; Serrano, Manuel
15
3
382 -
394
2012
Key contribution of CPEB4-mediated translational control to cancer progression
Ortiz-Zapater, Elena; Pineda, David; Martinez-Bosch, Neus; Fernandez-Miranda, Gonzalo; Iglesias, Mar; Alameda, Francesc; Moreno, Mireia; Eliscovich, Carolina; Eyras, Eduardo; Real, Francisco X; Mendez, Raul; Navarro, Pilar
18
1
83 -
90
2012
The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress
Joaquin M; Gubern A; González-Nuñez D; Josué Ruiz E; Ferreiro I; De Nadal E; Nebreda A; Posas F
31
13
2952 -
2964
2012
Structure of triplex DNA in the Gas phase
Arcella A; Portella G; Ruiz M; Eritja R; Vilaseca M; Gabelica V; Orozco M
134
15
6596 -
6606
2012
Deleterious effects of neuronal accumulation of glycogen in flies and mice
Duran, Jordi; Florencia Tevy, Maria; Garcia-Rocha, Mar; Calbo, Joaquim; Milan, Marco; Guinovart, Joan J
4
8
719 -
729
2012
Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia
Dekanty, Andres; Barrio, Lara; Muzzopappa, Mariana; Auer, Herbert; Milan, Marco
109
50
20549 -
20554
2012
A Role for tRNA Modifications in Genome Structure and Codon Usage
Novoa, Eva Maria; Pavon-Eternod, Mariana; Pan, Tao; de Pouplana, Lluis Ribas
149
1
202 -
213
2012
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis.
Sebastián D, Hernández-Alvarez MI, Segalés J, Sorianello E, Muñoz JP, Sala D, Waget A, Liesa M, Paz JC, Gopalacharyulu P, Oreši? M, Pich S, Burcelin R, Palacín M, Zorzano A
109
14
5523 -
5528
2012
P-Stereogenic Secondary Iminophosphorane Ligands and Their Rhodium(I) Complexes: Taking Advantage of NH/PH Tautomerism
Leon, Thierry; Parera, Magda; Roglans, Anna; Riera, Antoni; Verdaguer, Xavier
51
28
6951 -
6955
2012
Fine-tuning the p-p Aromatic Interactions in Peptides: Somatostatin Analogues Containing Mesityl Alanine
Martin-Gago, Pablo; Gomez-Caminals, Marc; Ramon, Rosario; Verdaguer, Xavier; Martin-Malpartida, Pau; Aragon, Eric; Fernandez-Carneado, Jimena; Ponsati, Berta; Lopez-Ruiz, Pilar; Cortes, Maria Alicia; Colas, Begona; Macias, Maria J; Riera, Antoni
51
8
1820 -
1825
2012
Combined bottom-up and top-down mass spectrometry analyses of the pattern of post-translational modifications of Drosophila melanogaster linker histone H1
Bonet-Costa, Carles; Vilaseca, Marta; Diema, Claudio; Vujatovic, Olivera; Vaquero, Alejandro; Omenaca, Nuria; Castejon, Lucia; Bernues, Jordi; Giralt, Ernest; Azorin, Fernando
75
13
4124 -
4138
2012
Drosophila melanogaster linker histone dH1 is required for transposon silencing and to preserve genome integrity
Vujatovic, Olivera; Zaragoza, Katrin; Vaquero, Alejandro; Reina, Oscar; Bernues, Jordi; Azorin, Fernando
40
12
5402 -
5414
2012
Viscoelastic response of contractile filament bundles
Besser A, Colombelli J, Stelzer EH, Schwarz US
83
5
051902 -
051902
2011
Isolation and in vitro expansion of human colonic stem cells
Jung, Peter; Sato, Toshiro; Merlos-Suarez, Anna; Barriga, Francisco M; Iglesias, Mar; Rossell, David; Auer, Herbert; Gallardo, Mercedes; Blasco, Maria A; Sancho, Elena; Clevers, Hans; Batlle, Eduard
17
10
1225 -
1227
2011
Specific GATA Factors Act as Conserved Inducers of an Endodermal-EMT
Campbell K; Whissell G; Franch-Marro X; Batlle E; Casanova J
21
6
1051 -
1061
2011
Controlling gene expression in response to stress
De Nadal E; Ammerer G; Posas F
12
12
833 -
845
2011
Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter
Rubio-Cosials A; Sidow J; Jiménez-Menéndez N; Fernández-Millán P; Montoya J; Jacobs H; Coll M; Bernadó P; Solà M
18
11
1281 -
U133
2011
Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress
Solé C; Nadal-Ribelles M; Kraft C; Peter M; Posas F; De Nadal E
30
16
3274 -
3284
2011
Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease
Valles-Ortega J; Duran J; Garcia-Rocha M; Bosch C; Saez I; Pujadas L; Serafin A; Cañas X; Soriano E; Delgado-García J; Gruart A; Guinovart J
3
11
667 -
681
2011
The F box protein partner of paired regulates stability of drosophila centromeric histone H3, CenH3 CID
Moreno-Moreno O; Medina-Giró S; Torras-Llort M; Azorín F
21
17
1488 -
1493
2011
Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling
Solanas G; Cortina C; Sevillano M; Batlle E
13
9
1100 -
U128
2011
A smad action turnover switch operated by WW domain readers of a phosphoserine code
Aragón E; Goerner N; Zaromytidou A; Xi Q; Escobedo A; Massagué J; Macias M
25
12
1275 -
1288
2011
Drosophila neuroblasts retain the daughter centrosome
Januschke J; Llamazares S; Reina J; Gonzalez C
2
1
243 -
2011
Distributed biological computation with multicellular engineered networks
Regot S; MacIa J; Conde N; Furukawa K; Kjellén J; Peeters T; Hohmann S; De Nadal E; Posas F; Solé R
469
7329
207 -
211
2011
The structure of a transcription activation subcomplex reveals how sigma(70) is recruited to PhoB promoters
Blanco, Alexandre G; Canals, Albert; Bernues, Jordi; Sola, Maria; Coll, Miquel
30
18
3776 -
3785
2011
The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
Merlos-Suarez, Anna; Barriga, Francisco M; Jung, Peter; Iglesias, Mar; Virtudes Cespedes, Maria; Rossell, David; Sevillano, Marta; Hernando-Momblona, Xavier; da Silva-Diz, Victoria; Munoz, Purificacion; Clevers, Hans; Sancho, Elena; Mangues, Ramon; Batlle, Eduard
8
5
511 -
524
2011
DDOR is an EcR coactivator that forms a feed-forward loop connecting insulin and ecdysone signaling
Francis V; Zorzano A; Teleman A
20
20
1799 -
1808
2010
Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1α/mitofusin-2 regulatory pathway in response to physical activity
Her?andez-Alvarez M; Thabit H; Burns N; Shah S; Brema I; Hatunic M; Finucane F; Liesa M; Chiellini C; Naon D; Zorzano A; Nolan J
33
3
645 -
651
2010
Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila
Janic A; Mendizabal L; Llamazares S; Rossell D; Gonzalez C
330
6012
1824 -
1827
2010
A dp53-dependent mechanism involved in coordinating tissue growth in Drosophila
Mesquita D; Dekanty A; Milán M
8
12
e1000566 -
2010
Hepatic overexpression of a constitutively active form of liver glycogen synthase improves glucose homeostasis
Ros S; Zafra D; Valles-Ortega J; García-Rocha M; Forrow S; Domínguez J; Calbó J; Guinovart J
285
48
37170 -
37177
2010
Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat
Jiménez-Menéndez N; Fernández-Millán P; Rubio-Cosials A; Arnan C; Montoya J; Jacobs H; Bernadó P; Coll M; Usón I; Solá M
17
7
891 -
893
2010
The miRNA machinery targets Mei-P26 and regulates Myc protein levels in the Drosophila wing
Herranz H; Hong X; Pérez L; Ferreira A; Olivieri D; Cohen S; Milán M
29
10
1688 -
1698
2010
Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control
Novoa I; Gallego J; Ferreira P; Mendez R
12
5
447 -
U82
2010
A Role of Receptor Notch in Ligand cis-Inhibition in Drosophila
Becam I; Fiuza UM; Arias AM; Milán M
20
6
554 -
560
2010
Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses
Geslain R, Cubells L, Bori-Sanz T, Alvarez-Medina R, Rossell D, Martí E, Ribas de Pouplana L
38
5
e30 -
e30
2010
Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain
Nadal M, Mas PJ, Blanco AG, Arnan C, Solà M, Hart DJ, Coll M
107
37
16078 -
16083
2010
Self-killing of melanoma cells by cytosolic delivery of dsRNA: Wiring innate immunity for a coordinated mobilization of endosomes, autophagosomes and the apoptotic machinery in tumor cells
Alonso-Curbelo D, Soengas MS
2010
The Ink4/Arf locus is a barrier for iPS cell reprogramming
Li, Han; Collado, Manuel; Villasante, Aranzazu; Strati, Katerina; Ortega, Sagrario; Canamero, Marta; Blasco, Maria A; Serrano, Manuel
460
7259
1136 -
U101
2009
Focus on the centre: The role of chromatin on the regulation of centromere identity and function
Torras-Llort M; Moreno-Moreno O; Azorín F
28
16
2337 -
2348
2009
Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure
Solon, Jerome; Kaya-Copur, Aynur; Colombelli, Julien; Brunner, Damian
137
7
1331 -
1342
2009
Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells
Tormo D, Checińska A, Alonso-Curbelo D, Pérez-Guijarro E, Cañón E, Riveiro-Falkenbach E, Calvo TG, Larribere L, et al, [corr. author] Soengas MS.
2009
An Operational RNA Code for Faithful Assignment of AUG Triplets to Methionine
Jones T; Brown C; Geslain R; Alexander R; de Pouplana L
29
3
401 -
407
2008