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Genome Data Science News

Scientific
Mutations in the "translators" of the human cell alter the reading of the genetic code in cancer and ageing
Scientific
A key genetic safeguard works differently across tissues and individuals
Scientific
New approach to decoding mutational signatures improves prediction of prognosis in ovarian cancer
Scientific
DiffInvex reveals how cancers rewire driver genes to beat chemotherapy
Scientific
‘Detective’ algorithm predicts best drugs for genetic disorders and cancer
Scientific
New patterns in cancer genetics point to tumour suppressor genes as potential therapeutic targets
Scientific
Characterization of mutational “coldspots” in the cancer genome
Institutional
World Cancer Day 2024: Highlights of IRB Barcelona’s cancer research
Scientific
Unravelling individual differences in DNA mutation risks
LUCIA's kick-off meeting
Institutional
Ambitious European project to elucidate the genomics and epigenomics of lung cancer
Dr. Fran Supek
Institutional
Dr. Fran Supek receives an ERC Consolidator grant to study cancer and aging-related DNA structural changes
Institutional
”la Caixa” Foundation backs machine learning to boost the efficacy of immunotherapies for the treatment of cancer
Media mentions
La edición genética mediante CRISPR/Cas9 puede provocar toxicidad celular e inestabilidad genómica - BioTech
Scientific
Gene editing via CRISPR/Cas9 can lead to cell toxicity and genome instability
Media mentions
Descubren 42 genes hereditarios que predisponen a un mayor riesgo de cáncer - El Periódico
Media mentions
Descubren 42 genes hereditarios que elevan la probabilidad de desarrollar cáncer - El Mundo
Scientific
Hereditary factors that increase the likelihood of cancer mutations detailed in new study
Media mentions
Crean un algoritmo que predice la respuesta de los tumores a los fármacos - La Vanguardia
Scientific
Not individual genes but the “mutational signatures” of many genes hold the key to better cancer therapies
Scientific
One mutation or two? Researchers discover why some genes require one or two hits to promote cancer
Landscape of synthetic lethal genes upon APOBEC activation in lung cancer cells.
Scientific
A potential target to treat lung cancer identified
Institutional
IRB Barcelona to participate in the DECIDER project, aimed at improving diagnostics and treatment of ovarian cancer
The discovered type of diffuse hypermutation is called "mutation fog". (Dave Hoefler, Unsplash)
Scientific
Mutations in cancer genomes: foggy with a chance of thunderstorms
Marina Salvadores, PhD student at IRB Barcelona and first author of the study published in Science Advances.
An interview with Marina Salvadores, PhD student at IRB Barcelona
Scientific
80% of the cancer cell lines used in research closely resemble their tissue-of-origin
Predictive decision trees optimized to decide if a cancer mutation will become visible to the immune system. Rik G.H. Lindeboom, Radboud University.
Media mentions
A new algorithm identifies the patients that will most benefit from immunotherapy
Fran Supek, head of the Genome Data Science laboratory at IRB Barcelona
Institutional
Fran Supek becomes an EMBO Young Investigator
Predictive decision trees optimized to decide if a cancer mutation will become visible to the immune system. Rik G.H. Lindeboom, Radboud University.
Scientific
Scientists build machine learning-based algorithm to predict which cancer patients benefit from immunotherapy
A invasive front of highly aggressive tumour cells (in green). Confocal microscopy image. Alexandra Avgustinova, IRB Barcelona.
Media mentions
Top 10 scientific hits of 2018
Image: IRB Barcelona
Media mentions
A study suggests that epigenetic therapies could lead to the appearance of aggressive tumors